The 1992 Score set contains 893 cards issued in two series. Cards 395-424/736-772/914-877 feature Rookie Prospects, 425-428/784-787 No-Hit Club, 429-430 Highlights, 431-440 AL All-Stars, 441-442/883-893 Dream Team, 773-782 NL All-Stars, 783,795-797 Highlights, 799-810 Draft Picks and 878-882 Memorabilia.

1992 Score set features Hall-of-Famers such as: Nolan Ryan, Ozzie Smith, Rickey Henderson, Eddie Murray, Robin Yount, George Brett, Paul Molitor, Sparky Anderson, Carlton Fisk, Dave Winfield, Gary Carter, Eddie Murray, Dennis Eckersley, Goose Gossage, Cal Ripken Jr. Tony Gwynn, Ryne Sandberg, Wade Boggs, Kirby Puckett and Pete Rose.

Other 1992 stars include: Barry Bonds, Vinny Castilla and Manny Ramirez.